Stability-Indicating HPLC Determination of Gemcitabine in Pharmaceutical Formulations
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چکیده
منابع مشابه
Stability-Indicating HPLC Determination of Gemcitabine in Pharmaceutical Formulations
A simple, sensitive, inexpensive, and rapid stability indicating high performance liquid chromatographic method has been developed for determination of gemcitabine in injectable dosage forms using theophylline as internal standard. Chromatographic separation was achieved on a Phenomenex Luna C-18 column (250 mm × 4.6 mm; 5μ) with a mobile phase consisting of 90% water and 10% acetonitrile (pH 7...
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Article history: Received on: 17/09/2014 Revised on: 04/10/2014 Accepted on: 23/10/2014 Available online: 29/12/2014 A simple, RP-HPLC stability indicating method was developed for determination of mefenamic acid in pharmaceutical formulations and its degradation products using C8 column with the mobile phase containing mixture of Buffer : Acetonitrile + THF in the ratio of 55:45 v/v at a flow ...
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BACKGROUND A simple, specific, and fast stability indicating reverse phase liquid chromatographic method was established for instantaneous determination of moxifloxacin and prednisolone in bulk drugs and pharmaceutical formulations. RESULTS Optimum chromatographic separations among the moxifloxacin, prednisolone and stress-induced degradation products were achieved within 10 minutes by use of...
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The objective of the current study was to develop a validated stability-indicating assay method (SIAM) for risperidone after subjecting it to forced decomposition under hydrolysis, oxidation, photolysis, and thermal stress conditions. The liquid chromatographic separation was achieved isocratically on a symmetry C18 column (5 μm size, 250 mm × 4.6 mm i.d.) using a mobile phase containing methan...
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ژورنال
عنوان ژورنال: International Journal of Analytical Chemistry
سال: 2015
ISSN: 1687-8760,1687-8779
DOI: 10.1155/2015/862592